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Herodotus38 21 hours ago [-]
Great to see an example of concrete evidence that physicians made changes when the evidence showed a change was needed.
nikolay 17 hours ago [-]
This "evidence" is highly questionable. There's other evidence, i.e., that taking aspirin with DGL or vitamin C does not damage the stomach lining, have led to new formulations decades ago. In fact, high doses of aspirin have been sold in Europe combined with vitamin C for as long as I remember - Aspirin C by Bayer and Upsarin C by UPSA. There's other evidence, too, that aspirin protects against cancer.
Herodotus38 8 hours ago [-]
Sounds like you have additional and better evidence than the USPTF that made the changes in aspirin for primary prevention. They do have a method to give feedback, and based on my experience a person will respond to you personally. I suggest you submit your information to them.
Is this due to the stomach being empty? Does taking it at the end of a large meal better?
red-iron-pine 13 hours ago [-]
guessing ozympic, statins, and stomach staples + pretty reliable stats about causing internal bleeding
OutOfHere 17 hours ago [-]
Low-dode aspirin wrecks the stomach or small intestine anyway in many individuals, irrespective of its form. This strikes a lot sooner than internal bleeding. Both the chewable and the enteric-coated forms cause this injury at separate locations.
cucumber3732842 14 hours ago [-]
>in many individuals,
So then why are we not working to determine which individuals it is suitable for?
What is the alternative to aspirin for this use case and who benefits?
OutOfHere 14 hours ago [-]
One just finds out by trial and error, although the injury can take many months to manifest, and is slowly reversible upon cessation. As for the safer pharmaceutical alternative, clopidogrel is it, again in a sufficiently low dose, but it is not OTC.
clumsysmurf 12 hours ago [-]
Its probably best to talk to your doctor about a CAC score. I don't know if its possible to tell stable vs unstable plaque yet, but a higher CAC score may benefit from aspirin.
nikolay 17 hours ago [-]
It doesn't, as it doesn't dissolve in the stomach, thanks to its enteric coating.
https://www.uspreventiveservicestaskforce.org/uspstf/public-...
Is this due to the stomach being empty? Does taking it at the end of a large meal better?
So then why are we not working to determine which individuals it is suitable for?
What is the alternative to aspirin for this use case and who benefits?